Description

tert-Butyl n-[1-(Ethanesulfonyl)Piperidin-4-Yl]Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine and carbamate functional groups. This compound is of significant commercial importance for its role in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting specific enzymes and receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes during drug discovery.
• Protease & Kinase Inhibitor Synthesis: Serves as a core scaffold or precursor for compounds designed to inhibit proteases or kinases, which are important targets in oncology and inflammatory diseases.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of Active Pharmaceutical Ingredients (APIs) under cGMP conditions.
• Bioconjugation & Chemical Biology: Potential use in creating chemical probes or conjugates for studying biological pathways and target engagement.

Basic Information

Product Name	tert-Butyl n-[1-(Ethanesulfonyl)Piperidin-4-Yl]Carbamate
CAS No.	651056-52-9
Molecular Formula	C12H24N2O4S
Molecular Weight	292.40 g/mol
Synonyms	Boc-4-amino-1-(ethylsulfonyl)piperidine; 1-(Ethylsulfonyl)-4-[(tert-butoxycarbonyl)amino]piperidine; 4-[(tert-Butoxycarbonyl)amino]-1-(ethylsulfonyl)piperidine; tert-Butyl [1-(ethylsulfonyl)-4-piperidinyl]carbamate; 1-(Ethanesulfonyl)piperidin-4-amine, N-Boc protected; N-Boc-1-(ethylsulfonyl)piperidin-4-amine; 651056-52-9
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[1-(Ethanesulfonyl)Piperidin-4-Yl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can align with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.