Description

Pyrrolo[1,2-A]Pyrazin-1(2H)-One, Hexahydro-3-(Hydroxymethyl)-2-Methyl-, (3S,8As)- (9Ci) is a high-purity, stereochemically defined heterocyclic compound that serves as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique fused pyrrolopyrazinone scaffold, which is a privileged structure for developing novel bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to create new active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probe: Serves as a scaffold for creating tool compounds to study enzyme function and biological pathways in academic and industrial research.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial production of complex active pharmaceutical ingredients (APIs).
• Custom Synthesis & Contract Manufacturing: A starting material for specialized chemical service providers offering bespoke synthesis for client projects.

Basic Information

Item	Details
Product Name	Pyrrolo[1,2-A]Pyrazin-1(2H)-One, Hexahydro-3-(Hydroxymethyl)-2-Methyl-, (3S,8As)- (9Ci)
CAS No.	650578-01-1
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	(3S,8aS)-Hexahydro-3-(hydroxymethyl)-2-methylpyrrolo[1,2-a]pyrazin-1(2H)-one; (3S,8aS)-3-(Hydroxymethyl)-2-methylhexahydro-1H-pyrrolo[1,2-a]pyrazin-1-one; Hexahydro-3-(hydroxymethyl)-2-methyl-, (3S,8aS)-Pyrrolo[1,2-a]pyrazin-1(2H)-one; (3S,8aS)-2-Methyl-3-(hydroxymethyl)octahydropyrrolo[1,2-a]pyrazin-1-one; Chiral Pyrrolopyrazinone Derivative; Fused Bicyclic Lactam Intermediate
EINECS	Contact for details

Quality Control

Every batch of Pyrrolo[1,2-A]Pyrazin-1(2H)-One, Hexahydro-3-(Hydroxymethyl)-2-Methyl-, (3S,8As)- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding R&D and scale-up applications. Certificates of Analysis (COA) with full characterization data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the material under an inert atmosphere or with appropriate desiccants to maintain stability. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.