Description

(E)-5,6-Dimethoxy-3-(4-Hydroxybenzylidene)-1H-Indolin-2-One is a high-purity synthetic indolinone derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial building block and pharmacological scaffold for developing novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of new chemical entities, particularly for applications in oncology and neurological disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex molecules with potential biological activity.
• Chemical Research: Used as a standard or reference compound in method development and analytical studies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug candidates.
• Biochemical Research: Investigated for its interaction with various enzymes and receptors in biochemical assays.
• Academic Research: Employed in universities and research institutes for exploratory organic synthesis projects.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals.

Basic Information

Item	Details
Product Name	(E)-5,6-Dimethoxy-3-(4-Hydroxybenzylidene)-1H-Indolin-2-One
CAS No.	649758-61-2
Molecular Formula	C18H17NO4
Molecular Weight	311.33 g/mol
Synonyms	5,6-Dimethoxy-3-[(E)-4-hydroxybenzylidene]indolin-2-one; (E)-3-(4-Hydroxybenzylidene)-5,6-dimethoxyindolin-2-one; 3-[(E)-4-Hydroxybenzylidene]-5,6-dimethoxy-1H-indol-2-one; 5,6-Dimethoxy-3-(4-hydroxybenzylidene)indolin-2-one; (E)-3-(4-Hydroxybenzylidene)-5,6-dimethoxy-2-indolinone; 3-(4-Hydroxybenzylidene)-5,6-dimethoxy-1H-indole-2-one; 5,6-Dimethoxy-3-(4-hydroxybenzylidene)-1H-indole-2-one; 649758-61-2
EINECS	Contact for details

Quality Control

Our (E)-5,6-Dimethoxy-3-(4-Hydroxybenzylidene)-1H-Indolin-2-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen or argon to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.