Description

5-(6-Quinoxalinylmethylene)-2,4-Thiazolidinedione is a high-purity synthetic organic compound with the CAS registry number 648450-29-7. This heterocyclic compound is a valuable pharmacological research intermediate and building block in medicinal chemistry. It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting metabolic and inflammatory pathways.
• Research Chemical: Used in academic and industrial laboratories for biological screening and structure-activity relationship (SAR) studies.
• PPARγ Agonist Research: Serves as a core scaffold in the development of thiazolidinedione-based compounds for diabetes research.
• Kinase Inhibitor Development: Employed as a precursor in the synthesis of quinoxaline-containing molecules for oncology research.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis to create complex molecules for various high-value applications.

Basic Information

Item	Details
Product Name	5-(6-Quinoxalinylmethylene)-2,4-Thiazolidinedione
CAS No.	648450-29-7
Molecular Formula	C₁₂H₇N₃O₂S
Molecular Weight	257.27 g/mol
Synonyms	5-[(6-Quinoxalinyl)methylene]-2,4-thiazolidinedione; 5-(Quinoxalin-6-ylmethylene)thiazolidine-2,4-dione; TZD derivative; Quinoxaline-thiazolidinedione hybrid; GW-9662 analog; PPARγ ligand precursor; CAS 648450-29-7
EINECS	Contact for details

Quality Control

Every batch of our 5-(6-Quinoxalinylmethylene)-2,4-Thiazolidinedione is produced and tested under a strict quality management system. We ensure high chemical purity and batch-to-batch consistency through advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.