Description

1-Azabicyclo[2.2.1]Heptane-7-Carboxylic Acid, Hydrochloride is a high-purity, bicyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its unique bridged structure makes it a valuable intermediate for developing novel pharmaceuticals and fine chemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, leveraging its constrained bicyclic framework.
• Catalyst and Ligand Development: Serves as a precursor for creating novel chiral catalysts and ligands used in asymmetric synthesis.
• Chemical Research: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	1-Azabicyclo[2.2.1]Heptane-7-Carboxylic Acid, Hydrochloride
CAS No.	646055-94-9
Molecular Formula	C7H11NO2 • HCl
Molecular Weight	177.63 g/mol
Synonyms	7-Carboxy-1-azabicyclo[2.2.1]heptane hydrochloride; 1-Azabicyclo[2.2.1]heptane-7-carboxylic acid HCl; 7-(Carboxy)-1-azabicyclo[2.2.1]heptane hydrochloride; Endo-3-Aminobicyclo[2.2.1]heptane-2-carboxylic acid hydrochloride (related isomer); Bicyclic proline derivative hydrochloride; 2-Azabicyclo[2.2.1]heptane-3-carboxylic acid hydrochloride (structural analog); (1R,2R,4S)-1-Amino-2-hydroxy-7,7-dimethylbicyclo[2.2.1]heptane-1-carboxylic acid hydrochloride derivative
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[2.2.1]Heptane-7-Carboxylic Acid, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.