Description

6-(Chloropyrazin-2-Yl)Phenylamine is a high-purity, advanced pharmaceutical intermediate characterized by its chloropyrazine and aniline functional groups. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drug candidates and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential kinase inhibitors and other targeted small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides and fungicides that leverage the pyrazine moiety for biological activity.
• Material Science: Serves as a precursor for functionalized ligands and monomers in the creation of advanced polymers and coordination complexes.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Buchwald-Hartwig amination) to create complex biaryl amine structures for further functionalization.
• Academic & R&D: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	6-(Chloropyrazin-2-Yl)Phenylamine
CAS No.	642459-03-8
Molecular Formula	C10H8ClN3
Molecular Weight	205.64 g/mol
Synonyms	2-Chloro-6-anilinopyrazine; (6-Chloropyrazin-2-yl)aniline; 2-Anilino-6-chloropyrazine; 6-Chloro-2-anilinopyrazine; 6-Chloro-N-phenylpyrazin-2-amine; Benzenamine, 6-chloro-2-pyrazinyl-; 642459-03-8; 6-(Chloropyrazin-2-yl)benzenamine
EINECS	Contact for details

Quality Control

Our 6-(Chloropyrazin-2-Yl)Phenylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.