Description

[4-(4-Amino-2-Chloro-Phenyl)-Piperazin-1-Yl]-o-Tolyl-Methanone is a high-purity, advanced pharmaceutical intermediate featuring a complex piperazine-based molecular structure. This compound matters because it serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), enabling the development of targeted therapeutics. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for central nervous system (CNS) and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological receptors.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Incorporated into the final chemical structure of proprietary pharmaceutical compounds.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations for scale-up and cGMP production.
• Biochemical Research: Employed as a tool compound in biochemical assays to study specific enzyme or receptor interactions.
• Custom Synthesis: Serves as a starting material for the custom synthesis of more complex, tailored molecules for client-specific projects.

Basic Information

Product Name	[4-(4-Amino-2-Chloro-Phenyl)-Piperazin-1-Yl]-o-Tolyl-Methanone
CAS No.	640759-19-9
Molecular Formula	C18H20ClN3O
Molecular Weight	329.83 g/mol
Synonyms	1-[(4-Amino-2-chlorophenyl)piperazin-1-yl]-2-methylphenylmethanone; (4-Amino-2-chlorophenyl)(2-methylphenyl)(piperazin-1-yl)methanone; 4-(4-Amino-2-chlorophenyl)piperazin-1-yl)(o-tolyl)methanone; 640759-19-9; o-Tolyl[4-(4-amino-2-chlorophenyl)piperazin-1-yl]methanone; Methanone, [4-(4-amino-2-chlorophenyl)-1-piperazinyl]-o-tolyl-
EINECS	Contact for details

Quality Control

Our [4-(4-Amino-2-Chloro-Phenyl)-Piperazin-1-Yl]-o-Tolyl-Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Keep container tightly sealed under an inert atmosphere if long-term storage is required.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.