Description

Dapagliflozin CAS NO 639852-30-5 is a highly selective and potent sodium-glucose cotransporter 2 (SGLT2) inhibitor. This active pharmaceutical ingredient (API) is critical for the development and manufacturing of innovative oral antidiabetic medications. It is primarily used by pharmaceutical companies and research institutions in the production of treatments for type 2 diabetes mellitus, offering a mechanism of action that promotes glucose excretion via the kidneys.

Application

• Pharmaceutical API: Core active ingredient in the formulation of SGLT2 inhibitor class medications for managing type 2 diabetes.
• Drug Development: Used in preclinical and clinical research for developing new antidiabetic therapies and combination drugs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Formulation R&D: Employed in the research and development of various dosage forms, including tablets and fixed-dose combinations.
• Biochemical Research: Tool compound for studying SGLT2 receptor function, renal glucose handling, and related metabolic pathways.

Basic Information

Product Name	Dapagliflozin
CAS No.	639852-30-5
Molecular Formula	C21H25ClO6
Molecular Weight	408.87 g/mol
Synonyms	Dapagliflozin; BMS-512148; (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol; Forxiga API; Farxiga API; Dapagliflozin (anhydrous); Dapagliflozinum
EINECS	Contact for details

Quality Control

Our Dapagliflozin is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity pharmaceutical-grade specifications, typically referencing ICH guidelines and pharmacopeial standards. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any individual impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.