Description

n-[2-[4-(2-Methoxyphenyl)-1-Piperazinyl]Ethyl]-n-2-Pyridinyl-Cyclohexanecarboxamide Maleate is a high-purity, non-racemic chemical compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or active pharmaceutical ingredient (API) for investigating novel therapeutic pathways, particularly within the central nervous system. It is essential for pharmaceutical companies, contract research organizations (CROs), and academic institutions focused on developing next-generation neuropharmacological agents. Our supply is characterized by stringent quality control, batch-to-batch consistency, and reliable global logistics to support your R&D and scale-up processes.

Application

• Pharmaceutical Research & Development (R&D): Primary use as a key intermediate or reference standard in the synthesis and study of novel psychoactive pharmaceuticals.
• Neuropharmacology Studies: Investigation of receptor binding affinity and activity for targets associated with neurological and psychiatric conditions.
• Preclinical Development: Sourcing of high-purity material for in-vitro and in-vivo studies to establish pharmacokinetic and pharmacodynamic profiles.
• Process Chemistry & Scale-Up: Supplying consistent quality material for route scouting, optimization, and pilot-scale manufacturing of potential APIs.
• Analytical Reference Standard: Utilization in HPLC, LC-MS, and NMR for method development, validation, and quality control of related substances.
• Chemical Library Synthesis: Building block for creating focused libraries of analogs in medicinal chemistry programs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	n-[2-[4-(2-Methoxyphenyl)-1-Piperazinyl]Ethyl]-n-2-Pyridinyl-Cyclohexanecarboxamide Maleate
CAS No.	634908-75-1
Molecular Formula	C25H34N4O2 • C4H4O4
Molecular Weight	526.62 g/mol (Salt)
Synonyms	N-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexanecarboxamide maleate; Cyclohexanecarboxamide, N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-, (2Z)-2-butenedioate (1:1); A-381393 maleate; BMS-214778 maleate; A-381,393 maleate; Desvenlafaxine related compound maleate salt; Potential antipsychotic agent intermediate.
EINECS	Contact for details

Quality Control

Every batch of our n-[2-[4-(2-Methoxyphenyl)-1-Piperazinyl]Ethyl]-n-2-Pyridinyl-Cyclohexanecarboxamide Maleate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and strength, meeting the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting results from advanced techniques like HPLC, GC, NMR, and MS. Our quality commitment supports compliance with ICH guidelines and relevant regulatory frameworks for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.