Description

4-((4-Ethylpiperazin-1-Yl)Methyl)-3-(Trifluoromethyl)Aniline is a high-value aromatic amine derivative featuring a piperazine and a trifluoromethyl group, making it a versatile and potent building block in advanced organic synthesis. Its molecular structure is specifically engineered to act as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate sophisticated amine and fluorine-containing motifs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a building block for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of dyes, pigments, and other specialty aromatic compounds.
• Bioconjugation and Probe Chemistry: The reactive aniline group makes it suitable for creating fluorescent probes or for bioconjugation applications in diagnostic assays.
• Polymer Modification: Can be used to introduce functional amine groups into polymer chains to alter material properties.

Basic Information

Product Name	4-((4-Ethylpiperazin-1-Yl)Methyl)-3-(Trifluoromethyl)Aniline
CAS No.	630125-91-6
Molecular Formula	C14H20F3N3
Molecular Weight	287.33 g/mol
Synonyms	1-[4-Amino-2-(trifluoromethyl)benzyl]-4-ethylpiperazine; 3-(Trifluoromethyl)-4-[(4-ethyl-1-piperazinyl)methyl]aniline; 4-[(4-Ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)benzenamine; 4-(4-Ethylpiperazin-1-ylmethyl)-3-trifluoromethyl-aniline; 4-Amino-2-(trifluoromethyl)benzyl 4-ethylpiperazine; Benzenamine, 4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-((4-Ethylpiperazin-1-Yl)Methyl)-3-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency suitable for research and commercial-scale synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to brown solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.