Description

1-Piperazinecarboxaldehyde,3-Methyl-,(3R)-(9Ci) is a chiral, substituted piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a crucial chiral building block for the development of complex, biologically active molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for constructing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of novel, enantiomerically pure pesticides and herbicides, where specific stereochemistry is critical for efficacy and environmental safety.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals for clients.

Basic Information

Product Name	1-Piperazinecarboxaldehyde,3-Methyl-,(3R)-(9Ci)
CAS No.	627857-39-0
Molecular Formula	C6H12N2O
Molecular Weight	128.17 g/mol
Synonyms	(3R)-3-Methylpiperazine-1-carbaldehyde; (R)-3-Methylpiperazine-1-carboxaldehyde; 3-Methyl-1-piperazinecarboxaldehyde, (3R)-; 1-Piperazinecarboxaldehyde, 3-methyl-, (3R)-; (R)-3-Methyl-1-piperazinecarbaldehyde; (R)-3-Methylpiperazinecarbaldehyde; 627857-39-0; (R)-3-Methylpiperazine-1-carbaldehyde
EINECS	Contact for details

Quality Control

Our production of 1-Piperazinecarboxaldehyde,3-Methyl-,(3R)-(9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chemical purity. All materials are characterized by advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), chiral purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and moisture uptake. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.