Description

Piperazinone, 4-(Chloroacetyl)-3,3-Dimethyl- (9Ci) is a high-purity, functionalized piperazinone derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical sector. It is primarily needed by research chemists and process development teams in pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactive chloroacetyl group for further functionalization.
• Fine Chemical Production: Serves as a specialized building block for creating complex, high-value chemicals used in material science and catalysis.
• Academic & Contract Research: An essential reagent for medicinal chemistry programs and process chemistry optimization in university and CRO (Contract Research Organization) laboratories.
• Peptidomimetic Research: The piperazinone core is valuable for constructing peptidomimetics, which are molecules that mimic peptides for drug discovery.

Basic Information

Product Name	Piperazinone, 4-(Chloroacetyl)-3,3-Dimethyl- (9Ci)
CAS No.	626223-67-4
Molecular Formula	C8H13ClN2O2
Molecular Weight	204.65 g/mol
Synonyms	4-(Chloroacetyl)-3,3-dimethylpiperazin-2-one; 3,3-Dimethyl-4-(2-chloroacetyl)piperazin-2-one; 2-Piperazinone, 4-(chloroacetyl)-3,3-dimethyl- (9CI); 4-(2-Chloroacetyl)-3,3-dimethyl-2-piperazinone; 1-(2-Chloroacetyl)-4,4-dimethyl-3-oxopiperazine; 4-(Chloroacetyl)-3,3-dimethyl-2-piperazinone
EINECS	Contact for details

Quality Control

Our Piperazinone, 4-(Chloroacetyl)-3,3-Dimethyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.