Description

5-Bromo-3-(4-Fluoro-Phenyl)-Pyrazin-2-Ylamine is a high-purity, advanced pharmaceutical intermediate featuring a halogenated pyrazine core. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for drug discovery and process development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential kinase inhibitors and other small-molecule therapeutics targeting oncology and central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging its halogenated aromatic structure for bioactivity.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways in academic and industrial R&D.
• Material Science: Investigated as a monomer or precursor for constructing organic electronic materials and specialty polymers.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects under cGMP guidelines.

Basic Information

Product Name	5-Bromo-3-(4-Fluoro-Phenyl)-Pyrazin-2-Ylamine
CAS No.	625848-12-6
Molecular Formula	C10H7BrFN3
Molecular Weight	268.09 g/mol
Synonyms	5-Bromo-3-(4-fluorophenyl)pyrazin-2-amine; 2-Amino-5-bromo-3-(4-fluorophenyl)pyrazine; 5-Bromo-3-(p-fluorophenyl)-2-pyrazinamine; 625848-12-6; 5-Bromo-3-(4-fluoro-phenyl)-pyrazin-2-ylamine; 3-(4-Fluorophenyl)-5-bromopyrazin-2-amine
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-3-(4-Fluoro-Phenyl)-Pyrazin-2-Ylamine adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system supports development under research-grade to cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.