Description

(S)-3-Amino-1-n-Boc-Piperidine is a high-purity, chiral piperidine derivative and a crucial protected intermediate in organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules, ensuring the integrity of the final product's three-dimensional structure. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and fine chemicals where precise chirality is critical for biological activity.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of chiral drugs, especially in central nervous system (CNS) and antiviral therapeutic areas.
• Peptidomimetic Chemistry: Used to introduce constrained, chiral amine functionalities into peptide backbones to enhance stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as hydrogenation or cross-coupling reactions.
• Agrochemical Synthesis: Employed in the research and production of chiral pesticides and herbicides.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis and R&D: A versatile starting material for contract research organizations (CROs) and academic laboratories exploring novel chemical entities.

Basic Information

Product Name	(S)-3-Amino-1-n-Boc-Piperidine
CAS No.	625471-18-3
Molecular Formula	C10H20N2O2
Molecular Weight	200.28 g/mol
Synonyms	1-Boc-3-amino-(S)-piperidine; (S)-1-(tert-Butoxycarbonyl)-3-aminopiperidine; (S)-3-Amino-1-(tert-butoxycarbonyl)piperidine; tert-Butyl (S)-3-aminopiperidine-1-carboxylate; (S)-3-Amino-N-Boc-piperidine; (S)-1-N-Boc-3-aminopiperidine; (3S)-1-[(2-Methylpropan-2-yl)oxycarbonyl]piperidin-3-amine; BOC-3-Amino-(S)-piperidine
EINECS	Contact for details

Quality Control

Our (S)-3-Amino-1-n-Boc-Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.