Description

4-Piperidinone, 1-Acetyl-2,6-Dimethyl-, (2R,6R)-Rel- (9Ci) is a high-purity, stereochemically defined piperidinone derivative, serving as a critical chiral building block and advanced pharmaceutical intermediate. Its value lies in enabling the synthesis of complex molecules with precise stereochemistry, which is essential for developing active pharmaceutical ingredients (APIs) with targeted biological activity. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in central nervous system (CNS) and analgesic research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs).
• Analgesic Drug Synthesis: Used as a precursor in the synthesis pathway for certain classes of pain management medications.
• CNS-Active Compound Development: Employed in creating potential drug candidates targeting neurological disorders.
• Asymmetric Synthesis: Serves as a chiral template or starting material for constructing complex, stereoselective molecules.
• Medicinal Chemistry Research: Utilized in structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Process Chemistry & Scale-Up: Applied in developing and optimizing scalable synthetic routes for pharmaceutical manufacturing.

Basic Information

Item	Details
Product Name	4-Piperidinone, 1-Acetyl-2,6-Dimethyl-, (2R,6R)-Rel- (9Ci)
CAS No.	625086-90-0
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	1-Acetyl-2,6-dimethyl-4-piperidinone; (2R,6R)-1-Acetyl-2,6-dimethylpiperidin-4-one; rel-(2R,6R)-1-Acetyl-2,6-dimethyl-4-piperidinone; 4-Piperidinone, 1-acetyl-2,6-dimethyl-, (2R,6R)-rel-; 2,6-Dimethyl-1-acetyl-4-piperidinone; (R,R)-1-Acetyl-2,6-dimethylpiperidin-4-one (relative configuration)
EINECS	Contact for details

Quality Control

Our 4-Piperidinone, 1-Acetyl-2,6-Dimethyl-, (2R,6R)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.