Description

(R)-1,2-Dimethyl-Piperazine is a high-purity chiral piperazine derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a versatile chiral auxiliary and ligand for asymmetric catalysis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients with high stereoselectivity.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs, antivirals, and receptor antagonists.
• Asymmetric Catalyst Ligand: Used to construct chiral ligands for transition metal catalysts in enantioselective hydrogenation, cross-coupling, and other catalytic reactions.
• Agrochemical Synthesis: Employed in the research and development of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Chiral Resolution Agent: Serves as a resolving agent for the separation of racemic mixtures of carboxylic acids and other compounds.
• Research & Development: A valuable tool for medicinal chemists and process chemists in academia and industry for exploring new synthetic pathways and optimizing stereochemistry.
• Fine Chemical Production: Used in the manufacture of complex, high-value specialty chemicals requiring specific stereochemical configurations.

Basic Information

Product Name	(R)-1,2-Dimethyl-Piperazine
CAS No.	623586-02-7
Molecular Formula	C6H14N2
Molecular Weight	114.19 g/mol
Synonyms	(R)-1,2-Dimethylpiperazine; (R)-1,2-DMP; (2R)-1,2-Dimethylpiperazine; (R)-(-)-1,2-Dimethylpiperazine; (R)-DMP; (R)-Piperazine, 1,2-dimethyl-; (R)-Hexahydro-1,2-dimethylpyrazine; (R)-N,N'-Dimethylpiperazine
EINECS	Contact for details

Quality Control

Our (R)-1,2-Dimethyl-Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.