Description

Piperazine, 1-[(2S)-2,4-Diamino-1-Oxobutyl]- (9Ci) is a specialized chiral piperazine derivative, a high-value building block in advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, where its specific stereochemistry and functional groups enable precise molecular construction. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Peptidomimetic Chemistry: Used to construct peptide-like structures that mimic natural peptides, enhancing stability and bioavailability for therapeutic applications.
• Agrochemical Synthesis: Acts as a precursor in the synthesis of advanced pesticides and herbicides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Bioconjugation and Linker Chemistry: Utilized in the design of chemical linkers for antibody-drug conjugates (ADCs) and other bioconjugation strategies.
• Academic and Industrial R&D: A valuable reagent for chemical research in medicinal chemistry and process development laboratories.

Basic Information

Product Name	Piperazine, 1-[(2S)-2,4-Diamino-1-Oxobutyl]- (9Ci)
CAS No.	620947-80-0
Molecular Formula	C8H16N4O
Molecular Weight	184.24 g/mol
Synonyms	(2S)-2,4-Diamino-1-(piperazin-1-yl)butan-1-one; 1-[(2S)-2,4-Diaminobutanoyl]piperazine; L-2,4-Diaminobutyrylpiperazine; (S)-2,4-Diamino-N-(piperazin-1-yl)butyramide; 620947-80-0; Piperazine, 1-[(2S)-2,4-diamino-1-oxobutyl]-; A chiral diamino butanoyl piperazine derivative
EINECS	Contact for details

Quality Control

Our Piperazine, 1-[(2S)-2,4-Diamino-1-Oxobutyl]- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and cGMP manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.