Description

(R)-2-Methyl-1-Benzoylpiperazine is a chiral piperazine derivative characterized by its benzoyl-protected nitrogen and a stereogenic center at the 2-position. This compound serves as a versatile and valuable chiral building block in advanced organic synthesis, enabling the creation of enantiomerically pure molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• As a key chiral intermediate in the synthesis of pharmaceutical candidates, particularly for central nervous system (CNS) targets.
• Utilized in medicinal chemistry research for constructing libraries of novel bioactive molecules with defined stereochemistry.
• Acts as a precursor or ligand in asymmetric catalysis and synthesis.
• Employed in the research and development of agrochemicals requiring specific stereoisomers for optimal activity.
• Serves as a building block for advanced materials and specialty polymers where chirality influences material properties.
• Used in academic and industrial R&D for studying structure-activity relationships (SAR) and pharmacokinetic properties.

Basic Information

Product Name	(R)-2-Methyl-1-Benzoylpiperazine
CAS No.	619331-53-2
Molecular Formula	C12H16N2O
Molecular Weight	204.27 g/mol
Synonyms	(R)-1-Benzoyl-2-methylpiperazine; (R)-2-Methyl-1-(phenylcarbonyl)piperazine; (R)-N-Benzoyl-2-methylpiperazine; (R)-Benzoyl-2-methylpiperazine; (R)-2-Methylpiperazine-1-carboxaldehyde, N-benzoyl-; (R)-α-Methyl-1-benzoylpiperazine; (R)-Enantiomer of 2-Methyl-1-benzoylpiperazine
EINECS	Contact for details

Quality Control

Our (R)-2-Methyl-1-Benzoylpiperazine is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing identity, purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.