Description

(2S,5R)-1-Benzyl-2,5-Dimethyl-Piperazine CAS NO 618104-71-5 is a high-purity, stereochemically defined piperazine derivative. This compound is a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules, offering precise control over the three-dimensional structure of the final active ingredient. It is primarily required by research institutions and pharmaceutical companies engaged in the development of new drugs, particularly in areas such as central nervous system (CNS) agents and other therapeutic classes where stereochemistry is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), especially for CNS-targeting drugs.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce enantioselectivity.
• Medicinal Chemistry Research: Serves as a core scaffold for constructing compound libraries in structure-activity relationship (SAR) studies.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for candidate drugs during clinical development phases.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	(2S,5R)-1-Benzyl-2,5-Dimethyl-Piperazine
CAS No.	618104-71-5
Molecular Formula	C13H20N2
Molecular Weight	204.31 g/mol
Synonyms	1-Benzyl-2,5-dimethylpiperazine, (2S,5R)-; (2S,5R)-1-Benzyl-2,5-dimethylpiperazine; (2S,5R)-1-(Phenylmethyl)-2,5-dimethylpiperazine; 1-Benzyl-(2S,5R)-2,5-dimethylpiperazine; (2S,5R)-1-Bn-2,5-Dimethylpiperazine; Bn-DMP; Chiral 1-Benzyl-2,5-dimethylpiperazine
EINECS	Contact for details

Quality Control

Our (2S,5R)-1-Benzyl-2,5-Dimethyl-Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.