Description

(2R,5S)-1-Benzyl-2,5-Dimethylpiperazine is a high-purity, stereochemically defined chiral piperazine derivative. This compound serves as a critical chiral building block and ligand in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control in their synthetic routes.

Application

• As a chiral ligand or catalyst in asymmetric hydrogenation and other transition metal-catalyzed reactions.
• As a key chiral intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• As a building block for the development of novel chemical entities in medicinal chemistry and drug discovery programs.
• In the preparation of chiral auxiliaries and resolving agents for the separation of enantiomers.
• For research applications in organocatalysis and the study of stereoselective reaction mechanisms.
• As a precursor for specialty polymers and advanced materials requiring chiral centers.

Basic Information

Product Name	(2R,5S)-1-Benzyl-2,5-Dimethylpiperazine
CAS No.	618104-69-1
Molecular Formula	C13H20N2
Molecular Weight	204.31 g/mol
Synonyms	(2R,5S)-1-Benzyl-2,5-dimethylpiperazine; (2R,5S)-1-Benzyl-2,5-dimethyl-piperazine; 1-Benzyl-2,5-dimethylpiperazine, (2R,5S)-; (R,S)-1-Benzyl-2,5-dimethylpiperazine (specific to this isomer); 1-Benzyl-(2R,5S)-dimethylpiperazine; Bn-2,5-(R,S)-DMP; Chiral 1-Benzyl-2,5-dimethylpiperazine
EINECS	Contact for details

Quality Control

We supply (2R,5S)-1-Benzyl-2,5-Dimethylpiperazine in high chemical and enantiomeric purity grades suitable for demanding synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) providing detailed chiral purity (ee%), chemical purity (HPLC), and identity confirmation (NMR, IR) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.