Description

3-(2-Fluoro-Phenoxymethyl)-Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 614731-30-5. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering a key structural motif for modern drug discovery. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel central nervous system (CNS) active drugs and receptor-targeted therapies.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its unique fluorinated phenoxymethyl-piperidine structure.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex piperidine-based derivatives in medicinal chemistry.
• Life Science Research: Employed in academic and industrial R&D for pharmacological studies and biochemical assay development.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized compounds for client projects.

Basic Information

Product Name	3-(2-Fluoro-Phenoxymethyl)-Piperidine Hydrochloride
CAS No.	614731-30-5
Molecular Formula	C12H16FNO•HCl
Molecular Weight	245.72 g/mol (Free base: 209.26 g/mol)
Synonyms	3-[(2-Fluorophenoxy)methyl]piperidine hydrochloride; 1-(2-Fluorophenoxymethyl)-3-piperidine hydrochloride; Piperidine, 3-[(2-fluorophenoxy)methyl]-, hydrochloride (1:1); 3-(2-Fluorophenoxymethyl)piperidine HCl; 614731-30-5; 3-(2-Fluoro-phenoxymethyl)-piperidine HCl
EINECS	Contact for details

Quality Control

Our 3-(2-Fluoro-Phenoxymethyl)-Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.