Description

5-Chloro-3-Methoxypyrazine-2-Carbaldehyde is a versatile and high-value heterocyclic building block used in advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals due to its reactive aldehyde and halogenated pyrazine core. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Flavor and Fragrance Chemistry: Employed in the research of complex aroma chemicals, given the pyrazine moiety's significance in flavor profiles.
• Material Science Research: A building block for organic electronic materials and functional polymers.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	5-Chloro-3-Methoxypyrazine-2-Carbaldehyde
CAS No.	614730-18-6
Molecular Formula	C6H5ClN2O2
Molecular Weight	172.57 g/mol
Synonyms	5-Chloro-3-methoxypyrazine-2-carboxaldehyde; 2-Pyrazinecarboxaldehyde, 5-chloro-3-methoxy-; 3-Methoxy-5-chloropyrazine-2-carbaldehyde; 5-Chloro-3-methoxy-2-pyrazinecarbaldehyde; 614730-18-6; 5-Chloro-3-methoxypyrazinecarbaldehyde
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Methoxypyrazine-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere for long-term stability. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.