Description

2-Piperidinecarboxamide,n-(2,6-Dimethylphenyl)-3-Hydroxy-,(2S)-(9Ci) is a high-purity chiral intermediate of significant interest in advanced pharmaceutical synthesis. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for process development and scale-up activities requiring strict stereochemical control and reliable quality.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents.
• API Synthesis: Used as a critical building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients.
• Neurological Drug Development: Particularly relevant in the preclinical and clinical development of compounds targeting neurological pathways.
• Asymmetric Synthesis: Serves as a precursor or reagent in asymmetric catalytic processes to introduce stereochemical complexity.
• Process Chemistry & Scale-Up: Employed in process optimization and pilot-scale manufacturing for new drug candidates.
• Reference Standard: Can be utilized as an analytical reference standard for quality control and regulatory filings.

Basic Information

Product Name	2-Piperidinecarboxamide,n-(2,6-Dimethylphenyl)-3-Hydroxy-,(2S)-(9Ci)
CAS No.	612507-79-6
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	(2S)-N-(2,6-Dimethylphenyl)-3-hydroxypiperidine-2-carboxamide; 3-Hydroxy-N-(2,6-dimethylphenyl)-L-pipecolic acid amide; (2S)-3-Hydroxy-N-(2,6-dimethylphenyl)pipecolic acid amide; L-3-Hydroxy-N-(2,6-dimethylphenyl)pipecolic acid amide; (S)-3-Hydroxy-N-(2,6-dimethylphenyl)piperidine-2-carboxamide; (2S)-N-(2,6-Dimethylphenyl)-3-hydroxypipecolic acid amide; (S)-N-(2,6-Dimethylphenyl)-3-hydroxypiperidine-2-carboxamide
EINECS	Contact for details

Quality Control

Our 2-Piperidinecarboxamide,n-(2,6-Dimethylphenyl)-3-Hydroxy-,(2S)-(9Ci) is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. Each batch is characterized by techniques including HPLC, chiral analysis, and NMR to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.