Description

Piperazine, 2-[(4-Methylphenyl)Methyl]-, (2S)- (9Ci) is a chiral piperazine derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block, enabling the construction of complex molecules with precise stereochemistry. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug candidates.
• Asymmetric Synthesis: Utilized as a ligand or catalyst component in enantioselective reactions to produce optically pure compounds.
• Agrochemical Research: Serves as a structural motif in the design of new pesticides and herbicides with specific activity profiles.
• Material Science: Potential precursor for functionalized polymers or advanced materials requiring specific chiral centers.
• Academic & Industrial R&D: Used in chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies.

Basic Information

Product Name	Piperazine, 2-[(4-Methylphenyl)Methyl]-, (2S)- (9Ci)
CAS No.	612502-40-6
Molecular Formula	C13H20N2
Molecular Weight	204.31 g/mol
Synonyms	(2S)-2-[(4-Methylphenyl)methyl]piperazine; (S)-2-(4-Methylbenzyl)piperazine; (S)-2-(p-Tolylmethyl)piperazine; 2-[(4-Methylphenyl)Methyl]piperazine, (2S)-; (S)-1-(4-Methylbenzyl)piperazine (tautomeric form); L-2-(4-Methylbenzyl)piperazine; (S)-(-)-2-(4-Methylbenzyl)piperazine
EINECS	Contact for details

Quality Control

Our Piperazine, 2-[(4-Methylphenyl)Methyl]-, (2S)- (9Ci) is produced under strict quality management systems. We ensure high chiral purity and chemical integrity through advanced analytical techniques including HPLC, GC, and chiral chromatography. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request for every batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Consider storing under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.