Description

Piperazine, 2-[(3-Methylphenyl)Methyl]-, (2S)- (9Ci) is a chiral piperazine derivative of significant interest in advanced pharmaceutical synthesis. This compound serves as a crucial chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in the synthesis of complex, stereospecific molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug discovery.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• API Manufacturing: Used in the scalable production of specific, high-value active pharmaceutical ingredients requiring the (2S)- stereochemistry.
• Medicinal Chemistry Research: A valuable scaffold for constructing compound libraries in structure-activity relationship (SAR) studies.
• Fine Chemical Synthesis: Intermediate for producing specialized agrochemicals or performance chemicals where the specific stereochemistry imparts desired biological or physical properties.

Basic Information

Product Name	Piperazine, 2-[(3-Methylphenyl)Methyl]-, (2S)- (9Ci)
CAS No.	612502-35-9
Molecular Formula	C13H20N2
Molecular Weight	204.31 g/mol
Synonyms	(2S)-2-[(3-Methylphenyl)methyl]piperazine; (S)-2-(3-Methylbenzyl)piperazine; 2-[(3-Methylphenyl)Methyl]piperazine, (2S)-; (S)-1-(3-Methylbenzyl)piperazine (tautomeric form); L-2-(m-Tolylmethyl)piperazine; (S)-(-)-2-(3-Methylbenzyl)piperazine; Piperazine, 2-[(3-methylphenyl)methyl]-, (2S)-
EINECS	Contact for details

Quality Control

Our production of Piperazine, 2-[(3-Methylphenyl)Methyl]-, (2S)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and cGMP-grade standards where applicable. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Chiral Purity (Enantiomeric Excess)	≥98.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.