Description

Piperazine, 2-(2-Phenylethyl)-, (2S)- (9Ci) is a chiral piperazine derivative, a high-value building block in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. Pharmaceutical R&D and fine chemical manufacturers need this material for creating novel therapeutic agents with specific stereochemical requirements.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, especially in neurological and psychiatric applications.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce enantioselectivity.
• API Manufacturing: Serves as a building block in the multi-step synthesis of complex, stereochemically pure active pharmaceutical ingredients.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new chemical entities for biological activity.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals requiring a specific (S)-configured phenylethyl-piperazine moiety.

Basic Information

Product Name	Piperazine, 2-(2-Phenylethyl)-, (2S)- (9Ci)
CAS No.	612502-28-0
Molecular Formula	C12H18N2
Molecular Weight	190.28 g/mol
Synonyms	(2S)-2-(2-Phenylethyl)piperazine; (S)-2-(2-Phenylethyl)piperazine; (S)-2-Phenethylpiperazine; 2-[(2S)-2-Piperazinyl]ethylbenzene; 1-Phenethyl-2(S)-piperazine; L-2-(2-Phenylethyl)piperazine; (S)-(-)-2-(2-Phenylethyl)piperazine
EINECS	Contact for details

Quality Control

Our Piperazine, 2-(2-Phenylethyl)-, (2S)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >98%), enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.