Description

2,5-Piperazinedione, 3-[(3-Methylphenyl)Methyl]-, (3S)- (9Ci) is a chiral, substituted diketopiperazine derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a sophisticated building block for the development of novel bioactive molecules, particularly those targeting complex peptide-like structures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of potential drug candidates and specialized chemical intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially those with peptidomimetic properties.
• Medicinal Chemistry Research: Used as a constrained scaffold or building block for constructing compound libraries in drug discovery programs targeting various disease pathways.
• Peptidomimetic Synthesis: Facilitates the creation of diketopiperazine-based analogs, which are important for modulating peptide stability and bioavailability.
• Asymmetric Synthesis: Employed in stereoselective reactions to introduce the (3S)-chiral center into more complex molecular architectures.
• Biochemical Research: May serve as a reference standard or a tool compound in biochemical assays and proteomics studies.
• Fine Chemical Production: Integrated into multi-step synthetic routes for producing high-value, specialized chemicals for research and development.

Basic Information

Product Name	2,5-Piperazinedione, 3-[(3-Methylphenyl)Methyl]-, (3S)- (9Ci)
CAS No.	612502-11-1
Molecular Formula	C13H16N2O2
Molecular Weight	232.28 g/mol
Synonyms	(3S)-3-[(3-Methylbenzyl)]-2,5-diketopiperazine; (3S)-3-(3-Methylbenzyl)piperazine-2,5-dione; 3-[(3-Methylphenyl)Methyl]-2,5-piperazinedione, (3S)-; (S)-3-(3-Methylbenzyl)piperazine-2,5-dione; 612502-11-1; (3S)-3-(m-Tolylmethyl)piperazine-2,5-dione; A chiral diketopiperazine derivative
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedione, 3-[(3-Methylphenyl)Methyl]-, (3S)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity, meeting the exacting standards required for research and development applications. Comprehensive Certificates of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.