Description

Piperazine, 3-Methyl-1-(Trifluoroacetyl)-, (3S)- (9Ci) is a high-value, chiral piperazine derivative characterized by its trifluoroacetyl protecting group. This compound is a critical chiral building block and intermediate in modern synthetic organic chemistry, particularly for the development of active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of complex, stereochemically defined molecules, including potential drug candidates in therapeutic areas such as central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of novel Active Pharmaceutical Ingredients (APIs) and investigational new drugs.
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to construct complex molecular architectures with defined three-dimensional configurations.
• Medicinal Chemistry Research: Employed in drug discovery programs for lead optimization and the creation of focused compound libraries for biological screening.
• Chemical Biology: Can be utilized as a precursor for designing molecular probes to study biological pathways and enzyme functions.
• Process Chemistry Development: Acts as a starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Agrochemical Synthesis: Potential use as an intermediate in the development of advanced, chiral agrochemicals and pesticides.

Basic Information

Product Name	Piperazine, 3-Methyl-1-(Trifluoroacetyl)-, (3S)- (9Ci)
CAS No.	612493-84-2
Molecular Formula	C7H11F3N2O
Molecular Weight	196.17 g/mol
Synonyms	(3S)-3-Methyl-1-(trifluoroacetyl)piperazine; (S)-3-Methyl-1-(2,2,2-trifluoroacetyl)piperazine; 1-(Trifluoroacetyl)-3-methyl-(S)-piperazine; (S)-1-Trifluoroacetyl-3-methylpiperazine; 3-Methyl-1-(trifluoroacetyl)piperazine, (3S)-; (S)-3-Methyl-1-(trifluoroacetyl)piperazine; (S)-N-(Trifluoroacetyl)-3-methylpiperazine; 612493-84-2
EINECS	Contact for details

Quality Control

Our Piperazine, 3-Methyl-1-(Trifluoroacetyl)-, (3S)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and enantiomeric excess. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials such as strong bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.