Description

8-Chloro-2-(trifluoromethyl)imidazo[1,2-a]pyrazine is a high-value, heterocyclic organic compound featuring a fused imidazopyrazine core substituted with chloro and trifluoromethyl groups. This unique structure makes it a critical advanced intermediate for pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity imparted by the trifluoromethyl and heterocyclic motifs.
• Material Science Precursor: Serves as a specialty monomer or additive in the development of advanced organic electronic materials and functional polymers.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	8-Chloro-2-(trifluoromethyl)imidazo[1,2-a]pyrazine
CAS No.	611240-68-7
Molecular Formula	C7H3ClF3N3
Molecular Weight	221.57 g/mol
Synonyms	8-Chloro-2-(trifluoromethyl)imidazo[1,2-a]pyrazine; Imidazo[1,2-a]pyrazine, 8-chloro-2-(trifluoromethyl)-; 8-Chloro-2-trifluoromethylimidazo[1,2-a]pyrazine; 2-Trifluoromethyl-8-chloroimidazo[1,2-a]pyrazine; 611240-68-7; 8-Chloro-2-(trifluoromethyl)-imidazo[1,2-a]pyrazine
EINECS	Contact for details

Quality Control

We supply 8-Chloro-2-(trifluoromethyl)imidazo[1,2-a]pyrazine in high-purity grades suitable for research and development. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing all analytical results. We adhere to strict internal quality management protocols to support our clients' needs for reliable and traceable advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.