Description

Lobeglitazone CAS NO 607723-33-1 is a high-purity thiazolidinedione-class pharmaceutical compound. It serves as a potent and selective agonist for the peroxisome proliferator-activated receptor gamma (PPARγ), making it a critical active pharmaceutical ingredient (API) for metabolic disorder research and development. This compound is essential for pharmaceutical manufacturers and research institutions focused on developing next-generation therapeutics for type 2 diabetes and related conditions.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of anti-diabetic medications.
• Reference Standard for quality control and analytical method development in pharmaceutical laboratories.
• Biochemical Research for studying PPARγ signaling pathways and insulin sensitization mechanisms.
• Preclinical and Clinical Development of novel therapeutics for Type 2 Diabetes Mellitus (T2DM).
• Metabolic Disorder Studies investigating adipogenesis, glucose homeostasis, and lipid metabolism.
• Pharmaceutical Intermediates for the synthesis of more complex drug molecules or prodrugs.

Basic Information

Product Name	Lobeglitazone
CAS No.	607723-33-1
Molecular Formula	C19H20N2O5S
Molecular Weight	388.44 g/mol
Synonyms	Lobeglitazone; CKD-501; (RS)-5-{4-[2-(6-ethoxy-1-benzothiophen-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione; 5-[[4-[2-(6-ethoxy-2-benzothienyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione; 2,4-Thiazolidinedione, 5-[[4-[2-(6-ethoxy-2-benzothienyl)ethoxy]phenyl]methyl]-; Lobeglitazon; Lobeglitazona; Lobeglitazonum
EINECS	Contact for details

Quality Control

Our Lobeglitazone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.