Description

1-Piperazinepropanenitrile,4-[1-(4-Fluorophenyl)-2,5-Dioxo-3-Pyrrolidinyl]-(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Protease Inhibitor Research: Serves as a core structural component in the development of protease inhibitors, leveraging its pyrrolidinone and piperazine motifs.
• Chemical Biology & Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening and lead optimization.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules under cGMP conditions.
• Academic & Industrial R&D: Employed in academic laboratories and industrial R&D departments for exploratory synthesis and methodological development.

Basic Information

Product Name	1-Piperazinepropanenitrile,4-[1-(4-Fluorophenyl)-2,5-Dioxo-3-Pyrrolidinyl]-(9Ci)
CAS No.	606925-01-3
Molecular Formula	C17H19FN4O2
Molecular Weight	330.36 g/mol
Synonyms	4-[1-(4-Fluorophenyl)-2,5-dioxo-3-pyrrolidinyl]-1-piperazinepropanenitrile; 1-Piperazinepropanenitrile, 4-[1-(4-fluorophenyl)-2,5-dioxo-3-pyrrolidinyl]-; 4-(1-(4-Fluorophenyl)-2,5-dioxo-3-pyrrolidinyl)piperazine-1-propanenitrile; 606925-01-3 (CAS Name); 4-[1-(4-Fluorophenyl)-2,5-dioxopyrrolidin-3-yl]piperazine-1-propanenitrile
EINECS	Contact for details

Quality Control

Our production of 1-Piperazinepropanenitrile,4-[1-(4-Fluorophenyl)-2,5-Dioxo-3-Pyrrolidinyl]-(9Ci) adheres to stringent quality management systems, ensuring batch-to-batch consistency and high purity suitable for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.