Description

Pyrazinecarboxamide, n-[[3-(Trifluoromethyl)Phenyl]Methyl]- (9Ci) is a specialized fluorinated pyrazine derivative that serves as a high-value building block in advanced organic synthesis. This compound matters for its unique trifluoromethylphenyl moiety, which is critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in developing novel pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functional additive in the synthesis of specialty polymers and advanced materials.
• Ligand Synthesis: Employed in creating complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe: Utilized in the design of molecular probes for studying enzyme function and biological pathways.
• Fluorine Chemistry Studies: Acts as a model compound in academic and industrial research focused on fluorinated aromatic systems.

Basic Information

Product Name	Pyrazinecarboxamide, n-[[3-(Trifluoromethyl)Phenyl]Methyl]- (9Ci)
CAS No.	606132-12-1
Molecular Formula	C13H10F3N3O
Molecular Weight	281.24 g/mol
Synonyms	N-[[3-(Trifluoromethyl)phenyl]methyl]pyrazine-2-carboxamide; 2-Pyrazinecarboxamide, N-[[3-(trifluoromethyl)phenyl]methyl]-; N-[(3-Trifluoromethyl)benzyl]pyrazine-2-carboxamide; (3-Trifluoromethylbenzyl)carbamoylpyrazine; Pyrazine-2-carboxylic acid (3-trifluoromethyl-benzyl)-amide; 606132-12-1; UNII-9V6T2R8P4K
EINECS	Contact for details

Quality Control

Our Pyrazinecarboxamide, n-[[3-(Trifluoromethyl)Phenyl]Methyl]- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to fluoride and strong alkali; ensure it is stored separately from such materials to prevent decomposition. Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.