Description

Piperazine, 1-[(2,3-Dihydro-3-Oxo-4H-1,4-Benzoxazin-4-Yl)Acetyl]-4-(2,3-Dimethylphenyl)- (9Ci) is a specialized heterocyclic compound that serves as a high-value intermediate in advanced organic synthesis. Its complex molecular architecture, featuring fused benzoxazinone and substituted piperazine rings, makes it a critical building block for research and development in pharmaceutical chemistry. This compound is primarily sought by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of new drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used as a building block for creating novel molecules with potential herbicidal or pesticidal activity.
• Chemical Biology Probe Development: Serves as a scaffold for designing molecular probes to study enzyme function and biological pathways.
• Material Science Research: Potential monomer or precursor for advanced polymers with specific thermal or optical properties.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for methodological studies in heterocyclic and medicinal chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical and biotech companies in their discovery pipelines.

Basic Information

Product Name	Piperazine, 1-[(2,3-Dihydro-3-Oxo-4H-1,4-Benzoxazin-4-Yl)Acetyl]-4-(2,3-Dimethylphenyl)- (9Ci)
CAS No.	606118-30-3
Molecular Formula	C22H23N3O3
Molecular Weight	377.44 g/mol
Synonyms	1-[(2,3-Dihydro-3-oxo-4H-1,4-benzoxazin-4-yl)acetyl]-4-(2,3-dimethylphenyl)piperazine; 4-(2,3-Dimethylphenyl)-1-[(3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)acetyl]piperazine; 1-(2,3-Dihydro-3-oxo-4H-1,4-benzoxazin-4-yl)-2-[4-(2,3-dimethylphenyl)-1-piperazinyl]ethanone; N-(2,3-Dimethylphenyl)-4-[2-(2,3-dihydro-3-oxo-4H-1,4-benzoxazin-4-yl)-2-oxoethyl]piperazine-1-carboxamide precursor; Benzoxazinone-piperazine derivative.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. While typically supplied in research quantities, we ensure rigorous analytical characterization using techniques like HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and/or hygroscopic; therefore, handling under an inert atmosphere and desiccated conditions is recommended for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.