Description

4-Piperidinecarboxamide,n-(5-Fluoro-2-Methylphenyl)-1-Pyrazinyl-(9Ci) CAS NO 605639-94-9 is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry research.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural moiety for the development of new therapeutic agents.
• Chemical Biology Research: Used as a probe or building block in studying biological pathways and protein-ligand interactions.
• Contract Manufacturing: Supplied to CDMOs for scale-up synthesis under current Good Manufacturing Practice (cGMP) conditions for clinical trial material production.
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and pharmacology studies.
• Process Chemistry Optimization: Used in route scouting and process development to establish efficient, scalable manufacturing processes.

Basic Information

Product Name	4-Piperidinecarboxamide,n-(5-Fluoro-2-Methylphenyl)-1-Pyrazinyl-(9Ci)
CAS No.	605639-94-9
Molecular Formula	C17H17FN4O
Molecular Weight	312.34 g/mol
Synonyms	N-(5-Fluoro-2-methylphenyl)-1-(pyrazin-2-yl)piperidine-4-carboxamide; 1-(Pyrazin-2-yl)-N-(5-fluoro-2-methylphenyl)piperidine-4-carboxamide; 4-Piperidinecarboxamide, N-(5-fluoro-2-methylphenyl)-1-(2-pyrazinyl)-; 605639-94-9; UNII-7J7K8J3V6I; 7J7K8J3V6I; AOB67717; SCHEMBL21806227; DTXSID60636688
EINECS	Contact for details

Quality Control

Our 4-Piperidinecarboxamide,n-(5-Fluoro-2-Methylphenyl)-1-Pyrazinyl-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, purity, and impurity profile. We support development and commercial projects with material suitable for research use and can provide material manufactured under cGMP guidelines for advanced clinical stages upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.