Description

4-Piperidinecarboxamide,n-(3-Chloro-4-Fluorophenyl)-1-Pyrazinyl-(9Ci) CAS NO 605639-60-9 is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine and pyrazinyl functional groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• CNS Drug Development: Applied in the synthesis of potential therapeutic agents targeting neurological disorders, leveraging the piperidine moiety.
• Oncology Research: Utilized in the construction of molecular libraries for screening against various cancer cell lines and biological targets.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Piperidinecarboxamide,n-(3-Chloro-4-Fluorophenyl)-1-Pyrazinyl-(9Ci)
CAS No.	605639-60-9
Molecular Formula	C16H14ClFN4O
Molecular Weight	332.76 g/mol
Synonyms	N-(3-Chloro-4-fluorophenyl)-1-pyrazin-2-ylpiperidine-4-carboxamide; 1-Pyrazinyl-4-piperidinecarboxamide, N-(3-chloro-4-fluorophenyl)-; 4-Piperidinecarboxamide, N-(3-chloro-4-fluorophenyl)-1-pyrazinyl- (9CI); N-(3-Chloro-4-fluorophenyl)-1-(pyrazin-2-yl)piperidine-4-carboxamide; 605639-60-9; UNII-9K7J8F6F8I
EINECS	Contact for details

Quality Control

Our 4-Piperidinecarboxamide,n-(3-Chloro-4-Fluorophenyl)-1-Pyrazinyl-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.