Description

Piperazine, 1-(4-Methoxyphenyl)-4-[[1-(2-Pyrimidinyl)-3-Piperidinyl]Carbonyl]- (9Ci) CAS NO 605623-75-4 is a sophisticated piperazine derivative with a complex heterocyclic structure, serving as a critical advanced intermediate in modern organic synthesis. Its molecular architecture, featuring both piperazine and pyrimidine moieties, makes it a valuable scaffold for constructing novel bioactive compounds. This high-purity intermediate is primarily sought after by research institutions and pharmaceutical development teams focused on creating new therapeutic agents, particularly in areas requiring targeted molecular frameworks.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncological targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probe Development: Employed in the synthesis of molecular probes to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for fundamental studies in heterocyclic chemistry and novel synthetic methodology development.

Basic Information

Product Name	Piperazine, 1-(4-Methoxyphenyl)-4-[[1-(2-Pyrimidinyl)-3-Piperidinyl]Carbonyl]- (9Ci)
CAS No.	605623-75-4
Molecular Formula	C22H27N5O2
Molecular Weight	393.49 g/mol
Synonyms	1-(4-Methoxyphenyl)-4-[(1-pyrimidin-2-ylpiperidin-3-yl)carbonyl]piperazine; 4-[[1-(2-Pyrimidinyl)-3-piperidinyl]carbonyl]-1-(4-methoxyphenyl)piperazine; 1-(4-Methoxyphenyl)-4-[1-(pyrimidin-2-yl)piperidine-3-carbonyl]piperazine; UNII-8V5Q8F5011; 8V5Q8F5011; AOB67717; SR-01000915103; SCHEMBL21806227
EINECS	Contact for details

Quality Control

This high-value intermediate is produced under strict quality management systems to ensure batch-to-batch consistency and traceability. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research and development grade standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch upon request, supporting your regulatory and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.