Description

Piperazine, 1-(3-Methoxyphenyl)-4-[[1-(2-Pyrimidinyl)-4-Piperidinyl]Carbonyl]- (9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or probe in pharmacological assays to study receptor interactions and enzyme inhibition.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create complex molecules for advanced material science or agrochemical research.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	Piperazine, 1-(3-Methoxyphenyl)-4-[[1-(2-Pyrimidinyl)-4-Piperidinyl]Carbonyl]- (9Ci)
CAS No.	605621-27-0
Molecular Formula	C22H27N5O2
Molecular Weight	393.48 g/mol
Synonyms	1-(3-Methoxyphenyl)-4-[(1-pyrimidin-2-ylpiperidin-4-yl)carbonyl]piperazine; 4-[(1-Pyrimidin-2-ylpiperidin-4-yl)carbonyl]-1-(3-methoxyphenyl)piperazine; UNII-8K6U4Z8Q4F; 8K6U4Z8Q4F; 1-(3-Methoxyphenyl)-4-({1-[pyrimidin-2-yl]piperidin-4-yl}carbonyl)piperazine; 1-(3-Methoxyphenyl)-4-[[1-(2-pyrimidinyl)-4-piperidinyl]carbonyl]piperazine
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(3-Methoxyphenyl)-4-[[1-(2-Pyrimidinyl)-4-Piperidinyl]Carbonyl]- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.