Description

Piperazine, 1-Cyclohexyl-4-[(6-Fluoro-4-Hydroxy-3-Quinolinyl)Carbonyl]- (9Ci) is a sophisticated heterocyclic organic compound featuring a piperazine core linked to a fluorinated hydroxyquinoline moiety. This unique molecular architecture makes it a valuable pharmacophore and key intermediate in advanced organic synthesis. It is primarily sought after by pharmaceutical research and development organizations for the discovery and development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, or oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its piperazine and quinoline pharmacophores.
• Chemical Biology Probe Development: Acts as a scaffold for creating molecular probes to study biological pathways and protein interactions.
• High-Purity Reference Standard: Supplied as a certified reference material for analytical method development, validation, and quality control in pharmaceutical analysis.
• Custom Synthesis Starting Material: Utilized by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of complex molecules for clients.

Basic Information

Product Name	Piperazine, 1-Cyclohexyl-4-[(6-Fluoro-4-Hydroxy-3-Quinolinyl)Carbonyl]- (9Ci)
CAS No.	604773-14-0
Molecular Formula	C20H24FN3O2
Molecular Weight	357.43 g/mol
Synonyms	1-Cyclohexyl-4-[(6-fluoro-4-hydroxy-3-quinolinyl)carbonyl]piperazine; 4-[(6-Fluoro-4-hydroxy-3-quinolinyl)carbonyl]-1-cyclohexylpiperazine; 6-Fluoro-4-hydroxy-N-(1-cyclohexylpiperazin-4-yl)quinoline-3-carboxamide; 1-Cyclohexyl-4-(6-fluoro-4-hydroxyquinoline-3-carbonyl)piperazine; (6-Fluoro-4-hydroxyquinolin-3-yl)(4-cyclohexylpiperazin-1-yl)methanone
EINECS	Contact for details

Quality Control

Our high-purity pharmaceutical intermediates are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and mass spectrometry to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.