Description

Piperazine, 1-[(6-Ethoxy-4-Hydroxy-3-Quinolinyl)Carbonyl]- (9Ci) is a specialized quinoline derivative with a piperazine moiety, representing a high-value pharmaceutical intermediate. This compound matters for its role as a critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic chemistry. Pharmaceutical R&D and manufacturing organizations need this precise chemical to develop and produce next-generation medications, leveraging its unique molecular scaffold.

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs).
• Antimalarial Drug Research: Serves as a precursor or analog in the development of new quinoline-based antimalarial agents.
• Oncology Therapeutics: Investigated for use in creating targeted cancer therapies due to the quinoline core's biological activity.
• Chemical Biology & Proteomics: Utilized as a specialty reagent or linker in probe development for studying biological systems.
• Organic Synthesis Reference Standard: Employed as a high-purity standard for analytical method development and quality control in fine chemical production.

Basic Information

Product Name	Piperazine, 1-[(6-Ethoxy-4-Hydroxy-3-Quinolinyl)Carbonyl]- (9Ci)
CAS No.	604773-10-6
Molecular Formula	C17H19N3O3
Molecular Weight	313.35 g/mol
Synonyms	1-[(6-Ethoxy-4-hydroxy-3-quinolinyl)carbonyl]piperazine; 4-Hydroxy-6-ethoxy-3-quinolinecarboxylic acid piperazide; 6-Ethoxy-4-hydroxy-quinoline-3-carboxylic acid piperazide; (6-Ethoxy-4-hydroxyquinolin-3-yl)(piperazin-1-yl)methanone; Piperazine, 1-[(6-ethoxy-4-hydroxy-3-quinolinyl)carbonyl]-; Quinoline-3-carboxylic acid, 6-ethoxy-4-hydroxy-, piperazide
EINECS	Contact for details

Quality Control

Our production of Piperazine, 1-[(6-Ethoxy-4-Hydroxy-3-Quinolinyl)Carbonyl]- (9Ci) adheres to stringent quality management systems, ensuring batch-to-batch consistency for critical R&D and cGMP manufacturing applications. The material is characterized and released using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.