Description

Piperazine, 1-[(6-Ethoxy-4-Hydroxy-3-Quinolinyl)Carbonyl]-4-Methyl- (9Ci) is a specialized heterocyclic compound that serves as a key synthetic intermediate in advanced organic chemistry. Its value lies in its unique molecular architecture, combining a piperazine core with a quinoline moiety, which is crucial for constructing complex pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical development companies engaged in the synthesis of novel therapeutic agents, particularly in the areas of medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, or oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize the biological activity of quinoline and piperazine-based compounds.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of potential APIs, where its specific functional groups are modified to achieve desired therapeutic effects.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target identification due to its modifiable structure.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and process development for client-specific molecules.
• Academic Research: Employed in university and institutional laboratories for fundamental research in heterocyclic chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	Piperazine, 1-[(6-Ethoxy-4-Hydroxy-3-Quinolinyl)Carbonyl]-4-Methyl- (9Ci)
CAS No.	604772-99-8
Molecular Formula	C18H21N3O4
Molecular Weight	343.38 g/mol
Synonyms	1-[(6-Ethoxy-4-hydroxy-3-quinolinyl)carbonyl]-4-methylpiperazine; 4-Methyl-1-[(6-ethoxy-4-hydroxy-3-quinolinyl)carbonyl]piperazine; 1-(6-Ethoxy-4-hydroxyquinoline-3-carbonyl)-4-methylpiperazine; 4-Methylpiperazine-1-carboxylic acid 6-ethoxy-4-hydroxyquinolin-3-yl ester; (6-Ethoxy-4-hydroxyquinolin-3-yl)(4-methylpiperazin-1-yl)methanone
EINECS	Contact for details

Quality Control

Our Piperazine, 1-[(6-Ethoxy-4-Hydroxy-3-Quinolinyl)Carbonyl]-4-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be light-sensitive and hygroscopic; appropriate handling to minimize exposure to moisture and prolonged light is recommended to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.