Description

Piperazine, 1-[(4-Hydroxy-3-Quinolinyl)Carbonyl]- (9Ci) is a specialized heterocyclic compound that serves as a crucial advanced intermediate in modern organic synthesis. Its molecular architecture, combining piperazine and quinoline pharmacophores, makes it a valuable building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought by research institutions and pharmaceutical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, or oncology.
• API Synthesis: Serves as a core scaffold or a functionalized fragment in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop compounds with improved efficacy and safety profiles.
• Fine Chemical Production: Employed in the manufacture of high-value, low-volume specialty chemicals for research and diagnostic applications.
• Bioconjugation & Probe Development: Potential utility in creating fluorescent probes or bioconjugates for biochemical and cellular imaging studies, leveraging its quinoline moiety.

Basic Information

Product Name	Piperazine, 1-[(4-Hydroxy-3-Quinolinyl)Carbonyl]- (9Ci)
CAS No.	604772-60-3
Molecular Formula	C14H15N3O2
Molecular Weight	257.29 g/mol
Synonyms	1-(4-Hydroxy-3-quinolinyl)carbonylpiperazine; 1-(4-Hydroxyquinoline-3-carbonyl)piperazine; 4-Hydroxy-3-quinolinecarboxylic acid piperazide; (4-Hydroxyquinolin-3-yl)(piperazin-1-yl)methanone; Piperazine, 1-[(4-hydroxy-3-quinolinyl)carbonyl]-; 604772-60-3; UNII-9F8F6T4I4R
EINECS	Contact for details

Quality Control

Our production of Piperazine, 1-[(4-Hydroxy-3-Quinolinyl)Carbonyl]- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, critical for sensitive pharmaceutical R&D. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.