Description

Piperazine, 1-(4-Methylcyclohexyl)-4-[[4-(Trifluoromethyl)Phenyl]Sulfonyl]- (9Ci) is a specialized, high-value sulfonamide derivative of piperazine, designed for advanced pharmaceutical and agrochemical research and development. This compound matters for its role as a key synthetic intermediate or potential active pharmaceutical ingredient (API) precursor, offering a unique structural motif that combines a substituted piperazine core with a trifluoromethylphenyl sulfonyl group. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents or crop protection products with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS), oncology, and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, or insecticides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Chemical Biology Probe: Acts as a scaffold for creating tool compounds to study enzyme inhibition or receptor modulation in biochemical assays.
• Material Science Precursor: Potential use in the synthesis of advanced polymers or functional materials with specific sulfonamide properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects requiring this precise chemical entity.

Basic Information

Item	Detail
Product Name	Piperazine, 1-(4-Methylcyclohexyl)-4-[[4-(Trifluoromethyl)Phenyl]Sulfonyl]- (9Ci)
CAS No.	604762-08-5
Molecular Formula	C18H25F3N2O2S
Molecular Weight	390.47 g/mol
Synonyms	1-(4-Methylcyclohexyl)-4-[(4-trifluoromethyl)phenyl]sulfonyl]piperazine; 4-Methylcyclohexyl-piperazine sulfonamide derivative; N-(4-Methylcyclohexyl)-N'-[4-(trifluoromethyl)phenyl]sulfonyl]piperazine; 604762-08-5; 1-(4-Methylcyclohexyl)-4-[[4-(trifluoromethyl)phenyl]sulfonyl]piperazine
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(4-Methylcyclohexyl)-4-[[4-(Trifluoromethyl)Phenyl]Sulfonyl]- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements, from research to development scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.