Description

Piperidine, 4-(5-Fluoro-1H-Benzimidazol-1-Yl)-1-(Pyrazinylcarbonyl)- (9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapeutics, particularly in oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting kinase inhibition.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Biochemical Reagent: Employed in biochemical assays and as a tool compound for probing biological pathways and protein interactions.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for scale-up and cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Piperidine, 4-(5-Fluoro-1H-Benzimidazol-1-Yl)-1-(Pyrazinylcarbonyl)- (9Ci)
CAS No.	604742-09-8
Molecular Formula	C17H15FN6O
Molecular Weight	338.34 g/mol
Synonyms	4-(5-Fluoro-1H-benzimidazol-1-yl)-1-(pyrazinylcarbonyl)piperidine; 1-(Pyrazin-2-ylcarbonyl)-4-(5-fluoro-1H-benzimidazol-1-yl)piperidine; 4-(5-Fluoro-1H-benzo[d]imidazol-1-yl)-1-(pyrazine-2-carbonyl)piperidine; 604742-09-8; UNII-9I8S3959YF; 9I8S3959YF; AOB67717; SCHEMBL2180625; DTXSID60674423
EINECS	Contact for details

Quality Control

Our production of Piperidine, 4-(5-Fluoro-1H-Benzimidazol-1-Yl)-1-(Pyrazinylcarbonyl)- (9Ci) adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term stability, it is recommended to store under inert atmosphere at temperatures between 2°C and 8°C. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.