Description

Piperazine, 1-(3,5-Dimethoxybenzoyl)-4-(1-Ethyl-1H-Benzimidazol-2-Yl)- (9Ci) is a high-value, complex heterocyclic compound that serves as a critical intermediate in advanced pharmaceutical synthesis. Its unique molecular architecture, featuring a piperazine core linked to a benzimidazole and a dimethoxybenzoyl group, makes it an essential building block for developing novel active pharmaceutical ingredients (APIs). This compound is primarily sought by research institutions and pharmaceutical manufacturers engaged in the discovery and production of new therapeutic agents, particularly in areas requiring sophisticated chemical scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization processes.
• Active Pharmaceutical Ingredient (API) Synthesis: Incorporated into the final chemical structure of proprietary pharmaceutical compounds.
• Biochemical Research: Serves as a tool compound for investigating biological pathways and enzyme interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Item	Details
Product Name	Piperazine, 1-(3,5-Dimethoxybenzoyl)-4-(1-Ethyl-1H-Benzimidazol-2-Yl)- (9Ci)
CAS No.	604741-70-0
Molecular Formula	C22H26N4O3
Molecular Weight	394.47 g/mol
Synonyms	1-(3,5-Dimethoxybenzoyl)-4-(1-ethyl-1H-benzimidazol-2-yl)piperazine; 4-(1-Ethyl-1H-benzimidazol-2-yl)-1-(3,5-dimethoxybenzoyl)piperazine; UNII-9J1VK8J3F5; 9J1VK8J3F5; 1-(3,5-Dimethoxybenzoyl)-4-(1-ethylbenzimidazol-2-yl)piperazine; Piperazine, 1-(3,5-dimethoxybenzoyl)-4-(1-ethyl-1H-benzimidazol-2-yl)-
EINECS	Contact for details

Quality Control

Our production of Piperazine, 1-(3,5-Dimethoxybenzoyl)-4-(1-Ethyl-1H-Benzimidazol-2-Yl)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical applications. All materials are manufactured and tested in facilities that follow cGMP (current Good Manufacturing Practice) guidelines. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques like HPLC and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.