Description

5,6,7,8-Tetrahydroimidazo[1,5-A]Pyrazine Hydrochloride is a high-purity heterocyclic building block and pharmaceutical intermediate of significant commercial interest. Its unique fused bicyclic structure makes it a valuable scaffold in modern medicinal chemistry for the development of novel therapeutic agents. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile core structure for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Used in the preparation of more complex heterocyclic compounds due to its reactive imidazo-pyrazine framework.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of clinical trial materials and commercial APIs.
• Biochemical Research: Potential use as a ligand or probe in biochemical assays and enzyme inhibition studies.

Basic Information

Product Name	5,6,7,8-Tetrahydroimidazo[1,5-A]Pyrazine Hydrochloride
CAS No.	601515-49-5
Molecular Formula	C7H12ClN3
Molecular Weight	173.64 g/mol
Synonyms	Imidazo[1,5-a]pyrazine, 5,6,7,8-tetrahydro-, hydrochloride (1:1); 5,6,7,8-Tetrahydroimidazo[1,5-a]pyrazine HCl; 5,6,7,8-Tetrahydro-imidazo[1,5-a]pyrazine hydrochloride; THIP Hydrochloride; CAS 601515-49-5
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydroimidazo[1,5-A]Pyrazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.