Description

1-Stearoyl-2-Hydroxy-Sn-Glycero-3-Phosphoethanolamine is a high-purity, synthetic lysophospholipid, specifically a lysophosphatidylethanolamine (LPE). This compound is a critical building block in lipid biochemistry, valued for its role in membrane research and as a precursor for synthesizing more complex phospholipids. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise lipid components for drug delivery systems, biomimetic membranes, and biochemical studies.

Application

• Liposome & Drug Delivery System Formulation: A key component for creating stable liposomal carriers for targeted drug and gene delivery.
• Biomembrane & Model Membrane Research: Used to study membrane fluidity, protein-lipid interactions, and cell signaling pathways.
• Biochemical Reagent & Standard: Serves as a high-purity standard in analytical chromatography (HPLC, LC-MS) and enzymatic assays.
• Phospholipid Synthesis: Acts as a crucial synthetic intermediate for the production of complex, tailored phosphatidylethanolamines (PEs) and other phospholipid derivatives.
• Cosmetic & Dermal Formulations: Incorporated into advanced skincare products for its emulsifying and skin-barrier enhancing properties.
• Cell Culture & Media Supplements: Used as a lipid supplement in specialized cell culture media to support specific cell lines.

Basic Information

Item	Details
Product Name	1-Stearoyl-2-Hydroxy-Sn-Glycero-3-Phosphoethanolamine
CAS No.	69747-55-3
Molecular Formula	C23H48NO7P
Molecular Weight	481.60 g/mol
Synonyms	1-Stearoyl-LPE; 1-Stearoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine; Lysophosphatidylethanolamine (18:0); LPE(18:0); 1-Octadecanoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine; sn-Glycero-3-phosphoethanolamine, 1-stearoyl-2-hydroxy-; LysoPE(18:0); (2R)-2-Hydroxy-3-(octadecanoyloxy)propyl 2-(aminoethoxy)phosphate
EINECS	Contact for details

Quality Control

Every batch of 1-Stearoyl-2-Hydroxy-Sn-Glycero-3-Phosphoethanolamine is manufactured under strict quality management systems. We employ advanced analytical techniques including NMR, HPLC, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting research and cGMP-compliant applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. This material is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 98% (by titration)
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.