Description

3β-Hydroxy-14-Oxo-8,15-Cyclo-14,15-Seco-5β-Card-20(22)-Enolide CAS NO 69671-34-7 is a high-purity, structurally complex cardenolide derivative, a key intermediate in advanced pharmaceutical synthesis. Its precise stereochemistry and functional groups make it a critical building block for the research and development of novel therapeutic agents. This compound is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers specializing in steroid and cardiac glycoside chemistry.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel cardiac glycosides and other steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in studies investigating sodium-potassium ATPase (Na+/K+-ATPase) inhibition and related cardiac mechanisms.
• Medicinal Chemistry: Provides a sophisticated scaffold for structure-activity relationship (SAR) studies aimed at developing new therapeutic agents with targeted biological activity.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for the construction of complex natural product analogs and specialized chemical entities.

Basic Information

Product Name	3β-Hydroxy-14-Oxo-8,15-Cyclo-14,15-Seco-5β-Card-20(22)-Enolide
CAS No.	69671-34-7
Molecular Formula	C23H32O5
Molecular Weight	388.50 g/mol
Synonyms	3β-Hydroxy-14-oxo-8,15-cyclo-14,15-seco-5β-card-20(22)-enolide; 8,15-Cyclo-14,15-secocard-20(22)-enolide-3β,14-diol-14-one; 14,15-Secocardenolide derivative; Card-20(22)-enolide, 3β-hydroxy-14-oxo-8,15-cyclo-14,15-seco-5β-; 69671-34-7; Cardenolide intermediate; 8,15-Cyclocardenolide
EINECS	Contact for details

Quality Control

Our 3β-Hydroxy-14-Oxo-8,15-Cyclo-14,15-Seco-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.