Description

1,3-Dimethyl-7-[3-(n-Nicotinoyl-n-Methylamino)-2-Hydroxypropyl]-1H-Purine-2,6(3H,7H)-Dione is a high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound, with CAS number 69517-65-3, is valued for its complex purine-based structure which serves as a key building block for novel therapeutic agents. It is primarily sought by R&D laboratories and manufacturers in the pharmaceutical and biotechnology sectors engaged in the synthesis of specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, particularly those targeting neurological or cardiovascular pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new pharmacologically active compounds.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold or a key modified subunit in the production of target APIs under Good Manufacturing Practice (GMP) conditions.
• Biochemical Research: Employed as a standard or probe in biochemical assays to study enzyme interactions, particularly those involving purine-based systems.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	1,3-Dimethyl-7-[3-(n-Nicotinoyl-n-Methylamino)-2-Hydroxypropyl]-1H-Purine-2,6(3H,7H)-Dione
CAS No.	69517-65-3
Molecular Formula	C₁₇H₂₂N₆O₄
Molecular Weight	374.40 g/mol
Synonyms	7-[3-(N-Methylnicotinamido)-2-hydroxypropyl]-1,3-dimethylxanthine; 1,3-Dimethyl-7-[3-(N-methyl-3-pyridinecarboxamido)-2-hydroxypropyl]xanthine; Nicotinoyl-methyl-xanthine derivative; Xanthine, 7-[3-[(methyl-3-pyridinylcarbonyl)amino]-2-hydroxypropyl]-1,3-dimethyl-; 69517-65-3; 1,3-Dimethyl-7-(2-hydroxy-3-(N-methylnicotinamido)propyl)xanthine
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-7-[3-(n-Nicotinoyl-n-Methylamino)-2-Hydroxypropyl]-1H-Purine-2,6(3H,7H)-Dione is manufactured under strict quality systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥98% by HPLC), related substances, and other critical parameters is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.