Description

3-Hemisuccinate-25-Hydroxyvitamin D3 is a key synthetic intermediate and derivative of the biologically active form of Vitamin D. This compound is essential for research and development in the pharmaceutical and nutraceutical industries, where precise chemical modification is required for drug delivery and efficacy studies. It is primarily utilized by manufacturers and R&D laboratories focused on developing new therapeutic agents, diagnostic assays, and high-purity reference standards related to Vitamin D metabolism.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of advanced Vitamin D analogs and prodrugs for therapeutic applications.
• Reference Standard: Used as a high-purity calibrant in analytical methods (HPLC, LC-MS) for quality control and research.
• Biochemical Research: Employed in metabolic pathway studies, receptor binding assays, and pharmacokinetic research.
• Prodrug Development: The hemisuccinate ester group enhances solubility and bioavailability, making it valuable for formulating improved drug delivery systems.
• Diagnostic Reagent Manufacturing: Serves as a raw material in the production of reagents for clinical immunoassays measuring Vitamin D status.

Basic Information

Product Name	3-Hemisuccinate-25-Hydroxyvitamin D3
CAS No.	69511-19-9
Molecular Formula	C₃₀H₄₈O₅
Molecular Weight	488.70 g/mol
Synonyms	25-Hydroxyvitamin D3 3-hemisuccinate; Calcifediol 3-hemisuccinate; 25-Hydroxycholecalciferol 3-hemisuccinate; 3β-[(3-Carboxypropanoyl)oxy]-9,10-secocholesta-5,7,10(19)-trien-25-ol; 25(OH)D3-3-HS; 25-Hydroxy Vitamin D3 Hemisuccinate; 25-Hydroxy VD3 Hemisuccinate
EINECS	Contact for details

Quality Control

Our 3-Hemisuccinate-25-Hydroxyvitamin D3 is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for research and pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in DMSO, ethanol; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.