Description

3-(2-Chloro-6-Fluorophenyl)-5-Methylisoxazole-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound matters because it serves as a critical building block for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new products with enhanced efficacy.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the isoxazole moiety for biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the multi-step synthesis of complex APIs where the introduction of a halogenated phenyl-isoxazole group is required.
• Specialty Chemical Production: Acts as a building block for creating performance chemicals, dyes, and advanced materials.

Basic Information

Product Name	3-(2-Chloro-6-Fluorophenyl)-5-Methylisoxazole-4-Carbonyl Chloride
CAS No.	69399-79-7
Molecular Formula	C11H6Cl2FNO2
Molecular Weight	274.08 g/mol
Synonyms	3-(2-Chloro-6-fluorophenyl)-5-methyl-4-isoxazolecarbonyl chloride; 5-Methyl-3-(2-chloro-6-fluorophenyl)isoxazole-4-carbonyl chloride; 4-Isoxazolecarbonyl chloride, 3-(2-chloro-6-fluorophenyl)-5-methyl-; 2-Chloro-6-fluoro-α,5-dimethyl-4-isoxazoleacetoyl chloride (obsolete); 69399-79-7 (CAS Name); Isoxazole-4-carbonyl chloride derivative
EINECS	Contact for details

Quality Control

Our 3-(2-Chloro-6-Fluorophenyl)-5-Methylisoxazole-4-Carbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee consistency and traceability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening and protected from moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.